Ukadaulo wakuda wa endoscope (9) wodzitchinjiriza / antifungal

Ukadaulo wodzitchinjiriza komanso wothira chifunga wa ma endoscopes azachipatala ndichinthu chofunikira kwambiri chothandizira kukonza maopaleshoni ndikuchepetsa chiopsezo cha matenda. Kupyolera mu kupambana kwa sayansi yakuthupi ndi uinjiniya wapamtunda, imathetsa zowawa zamtundu wachikhalidwe monga chifunga ndi kuipitsidwa kwachilengedwe panthawi ya opaleshoni. Zotsatirazi ndikuwunika mwadongosolo kuchokera pamiyeso yaukadaulo, luso lazinthu, kufunikira kwachipatala, ndi chitukuko chamtsogolo:

1. Mbiri yaukadaulo ndi mfundo zowawa zachipatala

Zochepa za ma endoscopes osatsekedwa:

Intraoperative fogging: Mirror condensation chifukwa cha kusiyana kwa kutentha kwa thupi ndi kuwala kozizira (zochitika> 60%).

Kuipitsidwa kwachilengedwe: Kuchulukirachulukira pakuyeretsa chifukwa cha magazi ndi kumamatira kwa ntchofu (kutalikitsa nthawi ya opaleshoni ndi 15-20%).

Kuwonongeka kwa tizilombo toyambitsa matenda: Kupha tizilombo toyambitsa matenda mobwerezabwereza kumabweretsa kukalamba kwa zokutira pagalasi (kufupikitsa moyo ndi 30%).

2. Mfundo zamakono zamakono

(1) Ukadaulo wothana ndi chifunga

(2) Ukadaulo wodziyeretsa

3. Kupambana mu Sayansi Yazinthu

Zida zokutira zatsopano:

DuraShield ™ (Stryker Patent):

Mapangidwe angapo osanjikiza: kumatira pansi + pakati pa hydrophobic + pamwamba antibacterial

Kulekerera> 500 mkombero kutentha mkulu ndi kuthamanga kwambiri disinfection

EndoWet ® (ActivMed, Germany): zokutira za amphoteric polima, zotchingira madontho a magazi

Domestic Nano Clean (Shanghai Minimally Invasive): zokutira zophatikizika za graphene, ntchito ziwiri zopangira matenthedwe komanso antibacterial

Kuyerekeza kwa magwiridwe antchito:

4. Mtengo wa ntchito yachipatala

Ubwino wa Intraoperative:

Chepetsani kupukuta pafupipafupi: kuchokera pa avareji ya 8.3 pa unit mpaka nthawi 0.5 (kafukufuku wa J Hosp Infect 2023)

Kufupikitsa nthawi ya opaleshoni: Opaleshoni ya Laparoscopic imapulumutsa mphindi 12-15 (popeza palibe chifukwa chobwezera mobwerezabwereza ndikuyeretsa galasi)

Kupititsa patsogolo mawonekedwe azithunzi: Malo opangira opaleshoni mosalekeza amawonjezera kuzindikira kwa microvascular ndi 25%

Kuwongolera matenda m'chipatala:

3-log kuchepetsa katundu wachilengedwe (ISO 15883 test standard)

Kuipitsidwa kwa carbapenem resistant Escherichia coli (CRE) mu duodenoscopy kunatsika kuchokera 9% mpaka 0.2%.

5. Kuyimira katundu ndi opanga

6. Mavuto Aukadaulo ndi Mayankho

Zolepheretsa zomwe zilipo:

Kukhalitsa kwa zokutira:

Yankho: Ukadaulo wa Atomic Layer Deposition (ALD) kuti mukwaniritse zokutira wandiweyani wa nanoscale

Kuphimba kwapamwamba kwambiri:

Kupambana: Kupanga Mafilimu Ofanana ndi Plasma Enhanced Chemical Vapor Deposition (PECVD)

Biocompatibility:

luso: Biomimetic mussel protein adhesion technology (yopanda poizoni komanso yomanga kwambiri)

Mavuto azachipatala:

Kutentha chitetezo: kutentha kutsekedwa-kuwongolera kuwongolera (± 0.5 ℃ kulondola)

Kugwirizana kwa Disinfection: Kupanga zokutira zosagwirizana ndi hydrogen peroxide (zogwirizana ndi kutsekereza kwa plasma kotsika)

7. Kafukufuku waposachedwa

Kupambana Kwambiri mu 2023-2024:

Zodzikongoletsera zokha: zokutira zokhala ndi microencapsulated zopangidwa ndi Harvard University zomwe zimangotulutsa zida zodzikonzera pambuyo pazikwangwa (Sayansi 2023)

Photothermal antibacterial: Gulu lochokera ku Chinese Academy of Sciences lapanga zokutira zophatikizika za MoS ₂/graphene zokhala ndi chiwopsezo cha 100% pansi pa kuwala kwapafupi ndi infrared.

Zotchingira zosakhalitsa zosawonongeka: Chophimba cha PLGA chochokera ku ETH Zurich, Switzerland, chimasungunuka patatha maola awiri opaleshoni

Kupitilira kulembetsa:

FDA ivomereza endoscope yoyamba yasiliva ya ion antibacterial mu 2024 (Boston Sayansi)

China "Malangizo Owunika Ukadaulo Wopaka Tekinoloje ya Medical Endoscopes" yotulutsidwa mwalamulo (mtundu wa 2023)

8. Zochitika Zachitukuko Zamtsogolo

Mayendedwe a kuphatikiza kwaukadaulo:

Kuphimba kwanzeru:

PH sensitive discoloration (kuona chotupa micro acidic chilengedwe)

Thrombin imayambitsa kutulutsidwa kwa ma anti adhesion molecules

Kuyeretsa kwa roboti ya Nano:

Magnetron nano burashi imayenda yokha ndikuchotsa dothi pagalasi

kulosera zamsika:

Msika wapadziko lonse lapansi wokutira wokutira wapadziko lonse lapansi udzafika $1.8B pofika 2026 (CAGR 14.2%)

Kulowetsedwa kwa zokutira kwa antibacterial kudzapitirira 70% (makamaka duodenoscopy)

Chidule ndi mawonekedwe

Ukadaulo wodzitchinjiriza wodzitchinjiriza / anti chifunga ukukonzanso paradigm yogwiritsira ntchito endoscopic:

Mtengo wapano: Kuthana ndi zovuta zazikulu zachipatala monga chifunga chamkati ndi kuipitsidwa kwachilengedwe

Kupambana kwapakati: kusinthika kupita ku "kuyankha mwanzeru" zokutira zogwira ntchito

Cholinga chachikulu: Kukwaniritsa "zero kuipitsa, kukonza zero" pamwamba pa endoscopes

Ukadaulo uwu upitiliza kupititsa patsogolo chitukuko cha endoscopy kupita kumayendedwe otetezeka, ogwira mtima, komanso anzeru, pamapeto pake kukhala njira yoyeserera yazida zamankhwala kuti athe kukana matenda.