Ubuvuzi bwa endoscope yubuhanga (9) kwiyuhagira / kurwanya igihu

Ubuhanga bwo kwisukura no kurwanya ibicu bya endoskopi yubuvuzi nudushya twingenzi kugirango tunoze imikorere yo kubaga no kugabanya ibyago byo kwandura. Binyuze mu iterambere muri siyansi yubumenyi nubuhanga bwubutaka, ikemura ingingo yibanze yububabare bwa endoskopi gakondo nko guhuha no kwanduza ibinyabuzima mugihe cyo kubagwa. Ibikurikira nisesengura rifatika riva mubipimo byamahame ya tekiniki, guhanga ibintu, agaciro kivuriro, niterambere ryigihe kizaza:

1. Amateka ya tekiniki hamwe nububabare bwamavuriro

Imipaka ya endoskopi idafunze:

Igicu kidasanzwe: Kwirinda indorerwamo biterwa no gutandukanya ubushyuhe hagati yubushyuhe bwumubiri nisoko ikonje (incidence> 60%)

Kwanduza ibinyabuzima: Kongera ingorane zo gukora isuku bitewe no gufata amaraso na mucus (kumara igihe cyo kubagwa 15-20%)

Kwangiza kwanduza: Kwanduza imiti inshuro nyinshi biganisha ku gusaza gutwikira indorerwamo (igihe kigufi cyo kubaho 30%)

2. Amahame shingiro ya tekiniki

(1) Ikoranabuhanga rirwanya igihu

(2) Tekinoroji yo kwisukura wenyine

3. Iterambere mu bumenyi bwa siyansi

Ibikoresho byo gutwikira udushya:

DuraShield ™ (Stryker Patent):

Imiterere myinshi: imiterere yo hasi ya adhesion + hydrophobi yo hagati + antibacterial

Kwihanganira> inzinguzingo 500 z'ubushyuhe bwo hejuru hamwe no kwanduza umuvuduko mwinshi

EndoWet ® (ActivMed, Ubudage): Amphoteric polymer coating, anti maraso yanduza adsorption

Imbere muri Nano Isukuye (Shanghai Minimally Invasive): Graphene compating coating, imikorere ibiri yubushyuhe bwumuriro na antibacterial

Kugereranya ibipimo byerekana:

4. Agaciro gakoreshwa mubuvuzi

Inyungu zidasanzwe:

Mugabanye guhanagura inshuro: kuva ku kigereranyo cya 8.3 kuri buri gice kugeza kuri 0.5 (J Hosp Infect 2023)

Gabanya igihe cyo kubaga: Kubaga Laparoscopique bizigama iminota 12-15 (kuko nta mpamvu yo gusubira inyuma no guhanagura indorerwamo)

Gutezimbere ubwiza bwibishusho: Gukomeza kubaga umurima wo kubaga byongera umuvuduko wa mikorobe 25%

Kurwanya kwandura ibitaro:

Kugabanya ibiti 3 muburemere bwibinyabuzima (ISO 15883 ikizamini gisanzwe)

Igipimo cyanduye cya karbapenem irwanya Escherichia coli (CRE) muri duodenoscopi yagabanutse kuva kuri 9% igera kuri 0.2%

5. Guhagararira ibicuruzwa nababikora

6. Ibibazo bya tekiniki n'ibisubizo

Inzitizi ziriho:

Kuramba:

Igisubizo: Ikoranabuhanga rya Atomic Layer Deposition (ALD) kugirango ugere kuri nanoscale yuzuye

Ubuso bugaragara:

Iterambere: Imiterere ya firime imwe ya Plasma Yongerewe Imiti Yumuyaga (PECVD)

Biocompatibilité:

Guhanga udushya: Ikoranabuhanga rya biomimetic mussel protein yifata neza (idafite uburozi nubushobozi buhanitse)

Ibibazo by'amavuriro:

Umutekano wo gushyushya: ubushyuhe bufunze-kugenzura (± 0.5 ℃ ubunyangamugayo)

Kwanduza kwanduza: Gutezimbere hydrogène peroxide irwanya impuzu (ihujwe nubushyuhe buke bwa plasma sterilisation)

7. Amajyambere agezweho yubushakashatsi

Iterambere ryambukiranya imipaka muri 2023-2024:

Igikoresho cyo kwisana ubwacyo: microencapsulated coating yakozwe na kaminuza ya Harvard ihita irekura abashinzwe gusana nyuma yo gushushanya (Science 2023)

Antibacterial Photothermal: Itsinda ryaturutse mu Ishuri Rikuru ry’Ubumenyi ry’Ubushinwa ryateje imbere MoS ₂ / graphene ikomatanya ikoresheje igipimo cya sterisizione 100% munsi y’urumuri ruri hafi ya infragre

Gupfundikanya by'agateganyo: PLGA ishingiye kuri ETH Zurich, mu Busuwisi, ihita ishonga nyuma yamasaha 2 nyuma yo kubagwa

Iterambere ryo kwiyandikisha:

FDA yemeje bwa mbere ifeza ion antibacterial coated endoscope muri 2024 (Boston Scientific)

Ubushinwa "Amabwiriza yo gusuzuma ikoranabuhanga rya Coating for Medical Endoscopes" ryashyizwe ahagaragara ku mugaragaro (verisiyo ya 2023)

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Icyerekezo cyo guhuza ikoranabuhanga:

Ubwenge busubiza igisubizo:

PH ihindagurika cyane (visualisation yibibyimba micro acide ibidukikije)

Thrombin itera kurekura molekile zirwanya adhesion

Isuku ya robo ya Nano:

Magnetron nano brush yigenga yigenga kandi ikuraho umwanda hejuru yindorerwamo

guhanura isoko:

Ingano yisoko ya endoskopi yisi yose izagera kuri $ 1.8B muri 2026 (CAGR 14.2%)

Igipimo cyo kwinjira muri antibacterial coating kizarenga 70% (cyane cyane kuri duodenoscopi)

Incamake n'ibitekerezo

Kwiyuhagira / kurwanya ibicu byikoranabuhanga birahindura paradigmme yo gukoresha endoskopi:

Agaciro kagezweho: Gukemura ibibazo byingenzi byamavuriro nko gufatira hamwe no kwanduza ibinyabuzima

Ikiringo giciriritse: gutera imbere kugana "ubwenge bwo gusubiza ubwenge"

Intego nyamukuru: Kugera kuri "zeru zeru, kubungabunga zeru" hejuru ya endoskopi

Iri koranabuhanga rizakomeza guteza imbere iterambere rya endoskopi yerekeza ku cyerekezo cyizewe, gikora neza, kandi gifite ubwenge, amaherezo kikaba igisubizo cy’ibikoresho by’ubuvuzi kugira ngo birwanye indwara.